A) Generation of mice with loxP-flanked target genes (flox). (1

Mouse Modeling, Part 1: Genetically Engineered Mice

CRISPR/Cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method

Floxing - Wikipedia

Generation of a Matrix Gla (Mgp) floxed mouse, followed by conditional knockout, uncovers a new Mgp function in the eye

Targeting Vector Design

CRE Floxed Mice & more about lox-P

The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting

Cre-loxp system and Viral vector (AAV and adenovirus)-based Cre tools (AAV-Cre and Ad-Cre)

Gene-switch strategy using cre/LOX induced translational frameshift.

In Cre-Loxp system, does Cre only cut homozygous floxed allele?

Keratinocyte-specific knockout mice models via Cre–loxP recombination system

LentiFlash is an efficient and safe gene editing delivery technology for Cre-loxP models - Blog - Flash Therapeutics

LoxP-FRT Trap (LOFT): a simple and flexible system for conventional and reversible gene targeting, BMC Biology